Women's Health
Aciclovir
Aciclovir is used for treating chickenpox (varicella) or shingles (herpes zoster) and treating or suppressing genital herpes infections.



Drug Name
Aciclovir (acyclovir)
Drug-use
Acyclovir capsules for the treatment of chicken pox (varicella) or shingles (herpes zoster) and treating or suppressing genital herpes infections. It can also be applied to conditions other than die by your doctor.
How to use man
Use Acyclovir as directed by your doctor.
Take Acyclovir by mouth with or hobby room without food.
Drinking extra fluids while taking acyclovir are recommended.
Therapy with acyclovir beginning at the earliest sign or symptom of shingles or genital herpes (pain, burning, blisters).
If die treat acute outbreak, continue with acyclovir for the full year course of treatment, even if you feel better in a few days.
For oppressive treatment, acyclovir works best when it is put to Work Room same times each appendage.
Ask your health care provider any questions you can use it as acyclovir.
Drug Class and Mechanism
Acyclovir is an antiviral. It works by stopping viral replication to die. However, acyclovir does not eliminate the virus, is not a panacea and does not prevent transmission to others.
Missed dose
If you miss a dose of aciclovir and it regularly, take it as bare as possible. If it quick time for your next dose, skip the missed dose and die you go back to your regular dosing schedule. Do not take 2 doses at once.
Storage
Store acyclovir 68-77 graduate student F (20 and 25 graduate student C). Brief storage at temperatures of 59-86 graduate student F (15 and 30 C graduate student) is allowed. Store away from heat, moisture and light. Not in the bad. Keep Acyclovir out of the reach of children and pets.
Active mechanism
In order become effective, aciclovir has changed to go only to mono-phosphate by an enzyme, found only in viruses, called thymidine kinase (TK) is acyclovir become. Then his active triphosphate form is converted by enzymes in the human cells found.
CMV produces no thymidine kinase, so that the antiviral activity of aciclovir in CMV infections is bad.
Acyclovir triphosphate (AT) is the active form of the drug. It reduces the production of virus DNA, from competing with a natural material, Deoxyguanosine triphosphate, for the viral DNA polymerase enzyme. Installation of AT in the viral DNA completely prevents, that the new synthesis of DNA.
Viral DNA polymerase binds 10-30 sometimes stronger than the cellular DNA polymerase from AT. Diese means, acyclovir is not toxic.
Unfortunately, only about 15-20% of the dose are absorbed by the intestinal wall by acyclovir, that is, they often have to go like it only seized, Actively for two or three hours become in the blood stream.
aciclovir
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